Binglederry's Guide to Twitch

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Hello, I'm Binglederry. Here's my guide on twitch. I know some people will disagree with my setup, but I'm sure someone will get something out of it. Making it all worth while.
  
Lore: The city-state of Zaun is a twisted realm of science and magic run amok. The air is choked with pollution from the countless factories and magic labs that spew waste into the sky. As polluted as the sky is in Zaun, its subterranean levels are far worse. The waste products of Zaun's many different scientific and magical endeavors have flowed together in its sewers, mixing into a toxic and mysterious concoction. Rising up from this alchemical nightmare is a single plague rat.
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Unlike his lesser evolved cousins, Twitch (as he calls himself) can talk and read and interact with the world as well as any of the other sentient beings in Valoran. Twitch has come to the League of Legends to represent himself, the only one of his kind, on the Fields of Justice.
While Twitch's true motivations remain known only to him, his prowess in the arena is a matter of public record. As a creature of the sewers, he is able to blend in with the shadows and ambush unwary victims of his choosing. He has collected a significant quantity of the toxic soup that collects in Zaun's underground, and he coats his crossbow with it. The effect of being shot with one of Twitch's crossbow bolts is extremely debilitating. Even without his poison, he will outright infect those he chooses to attack, as is the nature of a plague rat. As an act of desperation, Twitch may rapidly unleash a flurry of bolts at his foes. He madly peppers a focused area, though with mercifully reduced damage.
 
Item Build:
1) Vampiric Scepter (Eventually building into a Bloodthirster)
2) Berserker Greaves
3) Madreds Bloodrazor
4) Infinity Edge
5) Black Cleaver
6) Bloodthirster

Runes: Some people prefer a mix of armor penetration, health, and physical damage runes, but with the item build I go; I'll have plenty of damage and crit. I personally find critical damage runes to be the best for twitch/shaco/gangplank.  

 
Summoner Spells: 
1) Now that rally was nerfed yet again, I perfer Ignite + Exhaust.
 
Abilities:
 
  (Passive) - Deadly Venom -
Twitch's attacks infect the target with Deadly Venom, which deal damage each second, stacks up to 6 times, and lasts up to 8 seconds.
 
  Q - Ambush -
Twitch hides in the shadows, waiting for a nearby enemy. If he attacks, he will gain bonus attack speed. After 1.25 seconds, Twitch becomes stealthed for 20 / 30 / 40 / 50 / 60 seconds. If Twitch attacks a unit while Stealthed, he gains 20 / 30 / 40 / 50 / 60 attack speed for up to 10 seconds, depending on how long he was stealthed before attacking.
 
  W - Debilitating Poison -
Infects a target with a crippling poison, slowing his movement speed.
Slows nearby enemy champions' move speed by 20%, plus 10% per Deadly Venom they have.
3 / 3 / 4 / 5 / 5 second duration.
 
  E - Expunge -
All nearby enemies secrete Twitch's toxic venoms from their bodies, dealing damage for each stack.
Deals 30 / 60 / 90 / 120 / 150 (+1 per ability power) magic damage to each nearby poisoned enemy, plus 20 / 30 / 40 / 50 / 60 additional damage per stack of Deadly Venom applied to them.
 
  R - Spray and Pray - (Ultimate)
Twitch closes his eyes and fires his crossbow as fast as he can, spraying piercing arrows ahead of him.
Twitch gains 40 / 80 / 120% attack speed and his attacks become 1000 range line missiles for 7 seconds, dealing 100% damage and poisoning all enemies hit.
 

Abilities:
Level 1) Rank 1 Expunge - E
Level 2) Rank 1 Stealth - Q
Level 3) Rank 2 Expunge - E
Level 4) Rank 1 Debilitating Poison - W
Level 5) Rank 3 Expunge - E
Level 6) Rank 1 Spray and Pray - R
Level 7) Rank 4 Expunge - E
Level 8) Rank 2 Stealth - Q
Level 9) Rank 5 Expunge - E
Level 10) Rank 3 Stealth - Q
Level 11) Rank 2 Spray and Pray - R
Level 12) Rank 4 Stealth - Q
Level 13) Rank 5 Stealth - Q
Level 14) Rank 2 Debilitating Poison - W
Level 15) Rank 3 Debilitating Poison - W
Level 16) Rank 3 Spray and Pray - R
Level 17) Rank 4 Debilitating Poison - W
Level 18) Rank 5 Debilitating Poison - W

Masteries: 21/0/9

Offense - 3/3 Deadliness
1/1 Cripple
4/4 Alacrity
3/4 Sorcery
3/3 Sunder
3/3 Brute Force
3/3 Lethality
1/1 Havoc
 
Utility - 3/3 Perseverence
1/3 Good Hands
4/4 Awareness
1/2 Utility Mastery
 
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